7/3/2023 0 Comments Dr stefan kaiser virginia mn![]() ![]() Accumulating evidence suggests that both factors are caused by a different neurobiological and behavioral mechanisms. Moreover, recent studies have shown that this distinction into two subgroups is clearly observable in patients, showing clinically meaningful differences in symptom presentation. According to the current consensus, they can be separated into two domains: the apathy domain, consisting of avolition, anhedonia, and asociality and the diminished expression domain, consisting of blunted affect and alogia. Negative symptoms (NS) are an integral feature of schizophrenia. This does not alter our adherence to PLOS ONE policies on sharing data and materials. None of these activities is related to the present study. Kaiser has received speaker’s fees from Janssen, Otsuka, Takeda, Lundbeck and Sandoz. PNT has received grant money from Pfizer. Lundbeck and has served as a consultant and/or speaker for AstraZeneca, Otsuka, Takeda, Eli Lilly, Janssen, Lundbeck, Novartis, Pfizer, Roche, and Servier. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: We have read the journal’s policy and the authors of this manuscript have the following competing interests: ES has received grant support from H. Additional data queries may be directed to Dr Matthias Kirschner ( This study was supported by the EMDO Stiftung (SK) and Hartmann Müller Stiftung (MH). This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the paper and its Supporting Information files. Received: DecemAccepted: Published: June 18, 2018Ĭopyright: © 2018 Stepien et al. PLoS ONE 13(6):Įditor: Therese van Amelsvoort, Maastricht University, NETHERLANDS (2018) Investigating the association of ventral and dorsal striatal dysfunction during reward anticipation with negative symptoms in patients with schizophrenia and healthy individuals. ![]() Citation: Stepien M, Manoliu A, Kubli R, Schneider K, Tobler PN, Seifritz E, et al. ![]()
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